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課程資訊 |
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課程名稱 |
神經發育與疾病 Neural Development and Disease | |
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開課學期 |
110-2 | |
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授課對象 |
生命科學院 跨領域神經科學國際研究生博士學位學程 | |
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授課教師 |
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課號 |
TIPGIN8011 | |
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課程識別碼 |
B49 D0300 | |
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班次 |
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學分 |
3.0 | |
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全/半年 |
半年 | |
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必/選修 |
選修 | |
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上課時間 |
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上課地點 |
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備註 |
總人數上限：30人 | |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 | |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
此課程主題包括神經發育的基本概念，有Neural induction, neuronal fate specification, neurite fate determination, dendrite development, axon guidance, synapse development 以及 circuit formation. 另外此課程也以特別講座的形式介紹 molecular and cellular aspects of neuroscience, neuron-glia interaction 和神經系統的疾病。 | |
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課程目標 |
在發育過程中產生健全的神經系統是我們能認知, 學習及進行各項活動的基礎 因此研究神經發育為相當重要的課題 | |
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課程要求 |
有修過分子生物學與細胞生物學的同學較適合修本課程 | |
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預期每週課後學習時數 |
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Office Hours |
備註： Class Time: 13:30-16:30, Wednesday Room: C101, Interdisciplinary Building, Academia Sinica | |
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指定閱讀 |
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參考書目 |
Development of the Nervous System (3rd) by Dan H. Sanes et al. | |
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評量方式 (僅供參考) |
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課程進度 |
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週次 |
日期 |
單元主題 |
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Week 1 |
2020/3/4 | Embryonic polarity and Induction, Dr. Jun-An Chen陳俊安 |
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Week 2 |
2020/3/11 | Fate specification and patterning, Dr. Shen-Ju Chou周申如 |
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Week 3 |
2020/3/18 | Determination of neurite fate, Dr. Pei-Lin Cheng鄭珮琳 |
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Week 4 |
2020/3/25 | Axon guidance, target selection and connection, Dr. Yung Shu Kuan 管永恕 |
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Week 5 |
2020/4/1 | Dendrite development, Dr. Cheng-Ting Chien 簡正鼎 |
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Week 6 |
2020/4/8 | Pre-synapse formation and function, Dr. Chi-Kuang Yao姚季光 |
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Week 7 |
2020/4/15 | Post-synapse formation, Dr. Shu-Ling Chiu 丘淑鈴 |
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Week 8 |
2020/4/22 | Ion channels in nervous system, Dr. Shi-Bing Yang 楊世斌 |
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Week 9 |
2020/4/29 | Neural circuits and behavior, Dr. Sue-Wei Lin林書葦 |
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Week 10 |
2020/5/6 | RNA biology in neural development and diseases, Dr. Guey-Shin Wang 王桂馨 & Dr. Woan-Yuh Tarn 譚婉玉 |
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Week 11 |
2020/5/13 | Midterm (development part—to circuit formation) |
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Week 12 |
2020/5/20 | Glia development, Dr. Henry Sun 孫以瀚 |
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Week 13 |
2020/5/27 | Glia in Huntinton’s disease, Dr. Yijuang Chern 陳儀莊 |
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Week 14 |
2020/6/3 | Centrosomes in brain development and disease, Dr. Tang K. Tang唐堂 |
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Week 15 |
2020/6/10 | Alzheimer’s disease (circuit spreading mechanism), Dr. Yung-Feng Liao廖永豐 |
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Week 16 |
2020/6/17 | Final exams (disease part), close-book style |